Oh, we have lots of those! There are some drugs that we use to treat high blood pressure work by causing vasodilation.

What’s really interesting about this new drug is:

“…iloprost is not only a vasodilator but also reduces oxidative stress, suggesting this dual mechanism of action could help explain its impressive potential as a frostbite treatment.”

It not only dilates blood vessels, it also directly treats reperfusion injury, which is really neat.

Yeah, I grew up in a small American town and my cousins were more like my siblings than my actual sister because they were the same age as me. We all fled that small town, so the next generation are all growing up not surrounded by extended family.

I think there are good and bad sides to it. It was nice to grow up surrounded by family with a strong sense of belonging. But my cousins’ children are growing up knowing people from far more diverse backgrounds than I ever had access to, which is good for them in a different way.

Overall, I think the effects are probably neutral

Making noise is the only way things actually get done in this world. Asking politely gets you nowhere. Squeaky wheel gets the grease and all that

Agreed, in my experience Tubi and Pluto both have very reasonable length, good quality ads. I declined to re-up on YouTube TV for NCAA football season this year specifically because I can stand their ads. At that price tier, they honestly expect me to sit through My Pillow ads??

Not autistic, but as a person with a chronic medical condition, damn this hits hard.

This is not something I had ever thought about before and I am also fascinated.

Just did. Won our vote Wednesday night 💪

As a Registered Nurse who is receiving actually successful medical treatments for ME/CFS from a big Boston hospital, thank you for sharing this.

I love the rhythm of this language. “Honga Tonga Honga Ha’apai” is so much fun to say.

From a volcano, per the source you linked:

"The Hunga Tonga-Hunga Ha’apai volcano — which violently erupted in January 2022 and blasted an enormous plume of water vapor into the stratosphere – likely contributed to this year’s ozone depletion. That water vapor likely enhanced ozone-depletion reactions over the Antarctic early in the season.

“If Hunga Tonga hadn’t gone off, the ozone hole would likely be smaller this year,” Newman said. “We know the eruption got into the Antarctic stratosphere, but we cannot yet quantify its ozone hole impact.”

Yes, but they’re trying to figure out if that’s where we’re at or if this is a temporary blip from the Honga Tonga Honga Ha’apai volcano.

Most volcanoes that size would cool the planet by ejecting a bunch of ash and sulfur dioxide into the upper atmosphere. But the Tonga volcano was underwater, so it threw a metric shitton of water vapor into the upper atmosphere instead, and this has a warming effect. This is part of the reason for the increase in precipitation on the West Coast of the US this year.

Add this volcano on top of the near simultaneous flip into an El Niño pattern, and they’re just not sure how permanent the warming we saw this year is going to be. But any way you go about it, this is really not good. We’ve just experienced dramatic warming from two things that we can’t predict and can’t control, on top of the part where we’re not doing nearly enough about the things we can control.

Select the “available for local pickup” option to weed out all the trash. Even if you’re buying to be shipped.

Use Amazon as a search engine, find what you need, then Google the manufacturer and buy it directly from them. You’d be surprised how many have free shipping . It’s usually not two day shipping, but what do you really need that fast?

If it’s electronics, buy online for local pickup at Best Buy. If it’s tools or house supplies, buy online for local pickup at Lowe’s or Home Depot. Buy online for local pickup at Target.

I haven’t purchased anything from Amazon in 4 years. It’s honestly way easier now than it was before Amazon started, but no one realizes that because Amazon got them locked in.

In real life, a restaurant can and will kick you out and ban you from the premises for wearing a swastika and saying you think minorities don’t deserve to live.

Ergo, being kicked off a company’s privately owned server for hate speech is EXACTLY the same amount of freedom they would have in real life.

Everyone loves censorship. Even you.

AI companies are most certainly making an effort to profit from the content they’re deriving from copyrighted works.

The kool-aid is laced, kid. You should put it down.

AI trained on plagiarized art created by real humans who were not compensated for work that AI companies are now making money on.

Aka stealing

It’s almost like people in the United States have the freedom to express their opinions on a matter. Imagine that!

This kind of passive bigotry is necessary for genocides to occur. It is the foundation on which the mechanisms of genocide are built.

It’s not just no good; it’s terrifying.

their staff faced extreme pressure to provide an immediate response. As such, their staff are instructed to process records requests in-store. CVS Health and Kroger apparently both argued that their staff are trained to respond to these requests and have access legal departments if they have questions.

Yeah, great corporate policy to force a bunch of criminally understaffed front line employees to try to add dealing with aggressive police officers to their daily tasks.